| 1518 |
The town of Kamenets was given right of self-government by Magdeburg Law. |
| 1519 |
The town of Ivatsevichi was mentioned in the chronicles for the first time. |
| 1527 |
Pinsk was besieged by Crimean Tatar troops. Tatars were defeated by Great getman Konstantin Ostrozhsky. |
| 1541 |
The national park of Belovezhskaya Pushcha was formed. Cutting of trees was banned since 1640.
It was the first forest reserve in the Central and Eastern Europe. |
| 1552 |
Logishin (Pinsk district) was mentioned for the first time. |
| 1552 |
Ruzhany (Pruzhany district) was mentioned for the first time. |
| 1553 |
The first printing-house in Belarus was founded in Brest. |
| 1555 |
Motol (Ivanovo district) was given right of self-government by Magdeburg Law. |
| 1561 |
A pharmacy was built in Pinsk. |
| 1566 |
The town of Malorita was mentioned in the chronicles
for the first time. It was the King village of Rita Malaya at that time. |
| 1575-1586 |
Stephan Batoriy (Stepan Batura) was the King of Poland and the Great Prince of the Great Lithuanian Princedom. |
| 1581 |
The town of Pinsk was given right of self-government by Magdeburg Law. |
| 1587-1632 |
Zhigimont III Vaza was the King of Poland and the Great Prince of the Great Lithuanian Princedom. |
| 1589 |
The towns of Kobrin and Pruzhany were given right of self-government by Magdeburg Law. |